A large-scale dataset of functional mouse ganglion cell layer responses

This work introduces the All-GCL dataset, a large-scale resource of functional two-photon Ca2+-imaging recordings with rich meta-data from more than 80,000 cells in the mouse ganglion cell layer. Compiled over nine years across 139+ experimental sessions, it includes light-evoked responses to various stimuli, functional group assignments for 46 cell types, and shows only small batch effects across experimenters, setups, and recording sessions — supporting population analyses, computational modeling, and machine learning development for vision neuroscience.

Recommended citation: Gonschorek, D., Oesterle, J., Zenkel, T., D'Agostino, F., Cai, C., Dyszkant, N., Szatko, K. P., Deja, F., Schwerd-Kleine, T., Arlinghaus, R., Franke, K., Zhao, Z., Schubert, T., Berens, P., & Euler, T. (2025). "A large-scale dataset of functional mouse ganglion cell layer responses." bioRxiv. 2025.12.04.691221.
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